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赵美萍 副教授
职 务:北京大学化学与分子工程学院
关注领域:新型亲和吸附材料的研制和分离机理研究 ,分子间相互作用的机理和分析应用研究 。

个人简介:

? ? 1968年生,?1990年、1993年、2002年先后获北京大学理学学士、硕士和博士学位。?1997-1998年,荷兰阿姆斯特丹大学环境与毒理化学系访问学者;?1998年,荷兰能源研究机构环境分析部访问学者。

主要职务:

现任博士生导师。

研究成果:

1、新型亲和吸附材料的研制和分离机理研究?
(1)?基于天然或重组特异性生物配体的亲和色谱的制备、分离机理研究及其在生命分析、环境检测和亚博足彩开户控制中的应用。?
(2)?智能分子印迹聚合物的制备、识别机理及其在分离、分析和催化方面的应用研究,突出理论预测及生物识别的化学模拟。??
2、分子间相互作用的机理和分析应用研究?
(1)?基于核酸-酶相互作用的基因点突变、DNA修饰和核酸酶活性等的实时荧光PCR检测方法研究。??
(2)?α,β-不饱和羰基化合物与核酸、蛋白质的相互作用及生物氧化性损伤标志物的检测方法研究。?

3、微流控芯片生化分离和高灵敏检测方法研究。
1、S?Zhou,?C?Zhang,?D?Wang?and?MP?Zhao,?Antigen?synthetic?strategy?and?immunoassay?development?for?
detection?of?acrylamide?in?foods,?TheAnalyst,?2008,?DOI:?10.1039/b716526a.??
2、ZD?Hua,?ZY?Chen,?YZ?Li,?MP?Zhao,?Thermosensitive?and?Salt-Sensitive?Molecularly?Imprinted??
Hydrogel?for?Bovine?Serum?Albumin,?Langmuir,?2008,?DOI:?10.1021/la703963f.??
3、ZY?Chen;?ZD?Hua;?L?Xu;?Y?Huang;?MP?Zhao;?YZ?Li,?Protein-responsive?imprinted?polymers?with??
specific?shrinking?and?rebinding,?Journal?of?Molecular?Recognition,?2008,?21,?71-77.??
4、ZY?Chen,?L?Xu,?Y?Liang,?JB?Wang,?MP?Zhao,?YZ?Li,?Polyethylene?glycol?diacrylate-based??
supermacroporous?monolithic?cryogel?as?high-performance?liquid?chromatography?stationary?phase?for??
protein?and?polymeric?nanoparticle?separation,?Journal?of?Chromatography?A,?2008,?1182,?128-131.??
5、MP?Zhao,?S?Zhou,?J?Yan?and?L?Li,?Immunochemical?Analysis?of?Endogenous?and?Exogenous?Estrogens,??
Current?Pharmaceutical?Analysis,?2007,?3,?25-38.??
6、ZY?Chen,?ZD?Hua,?J?Wang,?Y?Guan,?MP?Zhao,?YZ?Li,?Molecularly?imprinted?soluble?nanogels?as?a??
peroxidase-like?catalyst?in?the?oxidation?reaction?of?homovanillic?acid?under?aqueous?conditions,??
Applied?Catalysis?A:?General,?2007,?328,?252–258.??
7、Y?Guan,?RN?Shi,?XM?Li,?MP?Zhao,?YZ?Li,?Multiple?Binding?modes?for?dicationic?Hoechst?33258?to??
DNA,?J.?Phys.?Chem.?B,?2007,?111,?7336-7344.??
8、XM?Li,?Y?Huang,?C?Song,?MP?Zhao?and?YZ?Li,?Several?concerns?about?the?primer?design?in?the??
universal?molecular?beacon?real-time?PCR?assay?and?its?application?in?HBV?DNA?detection,?Anal??
Bioanal?Chem,?2007,?388,?979-985.??
9、JB?Mi,?J?Yan,?XJ?Ding,?ZQ?Guo,?MP?Zhao,?WB?Chang,?Production?and?characterization?of?monoclonal??
antibody?(IgM)?against?recombinant?human?erythropoietin,?Biomedical?and?Environmental?Sciences,??
2007,?20,?184-188.??
10、JB?Mi,?S?Wang,?XJ?Ding,?ZQ?Guo,?MP?Zhao?and?WB?Chang,?Efficient?purification?and??
preconcentration?of?erythropoietin?in?human?urine?by?reusable?immunoaffinity?column,?Journal?of??
Chromatography?B,?2006,?843,?125-130.??
11、YJ?Li,?MP?Zhao,?Simple?methods?for?rapid?determination?of?sulfite?in?food?products,?Food??
Control,?2006,?17,?975-980.??
12、JB?Mi,?XJ?Ding,?ZQ?Guo,?MP?Zhao?and?WB?Chang,?Screening?of?Carbohydrate-Specific?Phage??
Antibodies?Against?Recombinant?Human?Erythropoietin?(rHuEPO)?using?a?Phage?Display?Antibody??
Library:?Preliminary?Study,?Journal?of?Immunoassay?&?Immunochemistry,?2006,?27,?115-128.??
13、L?Li,?J?Yan,?MP?Zhao,?Improvement?of?the?performance?of?an?immunoaffinity?extraction?method?via??
region-specific?immobilization?of?IgG,?Journal?of?Chromatography?A,?2006,?1103(2),?350-355.??
14、JB?Mi,?J?Yan,?ZQ?Guo,?MP?Zhao,?WB?Chang,?Isolation?and?characterization?of?an?anti-recombinant??
erythropoietin?single-chain?antibody?fragment?using?a?phage?display?antibody?library,?Anal.??
Bioanal.?Chem.,?2005,?383,?218-223.??
15、J?Yan,?MP?Zhao,?YZ?Li,?An?efficient?immunoaffinity?chromatographic?method?for?extraction?and??
purification?of?papaverine?from?samples?of?pericarpium?papaveris?and?food?products,?Journal?of??
Separation?Science,?2005,?28,?1163-1170.??
16、J.?Yan,?JQ?Mi,?JT?He,?ZQ?Guo,?MP?Zhao,?WB?Chang,?Development?of?an?Indirect?Competitive?ELISA??
for?the?Determination?of?Papaverine,?Talanta,?2005,?66?(4),?1005-1011.??
17、JT?He,?ZW?Zhao,?ZH?Shi,?MP?Zhao,?YZ?Li,?WB?Chang,?Analysis?of?isoflavone?daidzein?in?Puerariae??
radix?with?micelle-mediated?extraction?and?preconcentration,?Journal?of?Agricultural?and?Food??
Chemistry,?2005,?53?(3),?518-523.??
18、J?Yan;?J?Wang;?MP?Zhao;?WB?Chang,?Determination?of?Papaverine?by?biotin-avidin?amplified?ELISA,??
Analytical?Letters,?2004,?37(14),?2977-2989.??
19、MP?Zhao,?Y?Liu,?YZ?Li,?XX?Zhang,?Wenbao?Chang,?Development?and?characterization?of?an??
immunoaffinity?column?for?the?selective?extraction?of?bisphenol?A?from?serum?samples,Journal?of??
Chromatography?B,?2003,?783(2),?401-410.??
20、MP?Zhao,?YZ?Li,?ZQ?Guo,?XX?Zhang?and?WB?Chang,?A?new?competitive?enzyme-linked?immunosorbe

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